Liver-specific deletion of RORα aggravates diet-induced nonalcoholic steatohepatitis by inducing mitochondrial dysfunction

Mitochondrial dysfunction may play a key role in the progression of steatosis to nonalcoholic steatohepatitis (NASH); however, the molecular mechanism that controls the structure and function of mitochondria in NASH is not clearly understood. Here, we demonstrated that RORα is a regulator of express...

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Detalles Bibliográficos
Autores principales: Kim, Hyeon-Ji, Han, Yong-Hyun, Na, Hyelin, Kim, Ju-Yeon, Kim, Taewook, Kim, Hye-Jin, Shin, Chanseok, Lee, Jung Weon, Lee, Mi-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700103/
https://www.ncbi.nlm.nih.gov/pubmed/29167529
http://dx.doi.org/10.1038/s41598-017-16077-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700103/
https://www.ncbi.nlm.nih.gov/pubmed/29167529
http://dx.doi.org/10.1038/s41598-017-16077-y

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