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Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening
In voltage-activated ion channels, voltage sensor (VSD) activation induces pore opening via VSD-pore coupling. Previous studies show that the pore in KCNQ1 channels opens when the VSD activates to both intermediate and fully activated states, resulting in the intermediate open (IO) and activated ope...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700111/ https://www.ncbi.nlm.nih.gov/pubmed/29167462 http://dx.doi.org/10.1038/s41467-017-01911-8 |