Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia

Chronic levodopa treatment leads to the appearance of dyskinesia in the majority of Parkinson’s disease patients. Neurovascular dysregulation in putaminal and pallidal regions is thought to be an underlying feature of this complication of treatment. We used microPET to study unilaterally lesioned 6-...

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Detalles Bibliográficos
Autores principales: Lerner, Renata P., Francardo, Veronica, Fujita, Koji, Bimpisidis, Zisis, Jourdain, Vincent A., Tang, Chris C., Dewey, Stephen L., Chaly, Thomas, Cenci, M. Angela, Eidelberg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700135/
https://www.ncbi.nlm.nih.gov/pubmed/29167476
http://dx.doi.org/10.1038/s41598-017-16228-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700135/
https://www.ncbi.nlm.nih.gov/pubmed/29167476
http://dx.doi.org/10.1038/s41598-017-16228-1

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