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Phospholipase A2-Responsive Phosphate Micelle-Loaded UCNPs for Bioimaging of Prostate Cancer Cells

We report the effective synthesis of biocompatible upconversion nanoparticles (UCNP)-loaded phosphate micelles and successful delivery of UCNPs to prostate cancer cells via secreted phospholipase A2 (sPLA-2) enzyme cleavage of the loaded micelles for the first time. The activity of the (sPLA-2) enzy...

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Detalles Bibliográficos
Autores principales: Sharipov, Mirkomil, Tawfik, Salah M., Gerelkhuu, Zayakhuu, Huy, Bui The, Lee, Yong-Ill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700164/
https://www.ncbi.nlm.nih.gov/pubmed/29167526
http://dx.doi.org/10.1038/s41598-017-16136-4