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Development and validation of scFv-conjugated affinity silk protein for specific detection of carcinoembryonic antigen

The production costs for monoclonal antibodies (MAbs) utilized in medical diagnostic kits are inevitably high because the MAbs are mostly obtained from hybridoma cell culture. Here, we report the development and validation of a novel affinity silk protein produced by transgenic silkworm technology a...

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Detalles Bibliográficos
Autores principales: Sato, Mitsuru, Kitani, Hiroshi, Kojima, Katsura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700171/
https://www.ncbi.nlm.nih.gov/pubmed/29167497
http://dx.doi.org/10.1038/s41598-017-16277-6