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Characterization of the early molecular changes in the glomeruli of Cd151(−/−) mice highlights induction of mindin and MMP-10

In humans and FVB/N mice, loss of functional tetraspanin CD151 is associated with glomerular disease characterised by early onset proteinuria and ultrastructural thickening and splitting of the glomerular basement membrane (GBM). To gain insight into the molecular mechanisms associated with disease...

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Detalles Bibliográficos
Autores principales: Naudin, Crystal, Smith, Brian, Bond, Danielle R., Dun, Matthew D., Scott, Rodney J., Ashman, Leonie K., Weidenhofer, Judith, Roselli, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700190/
https://www.ncbi.nlm.nih.gov/pubmed/29167507
http://dx.doi.org/10.1038/s41598-017-15993-3