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ZIKV infection regulates inflammasomes pathway for replication in monocytes

ZIKV causes microcephaly by crossing the placental barrier, however, the mechanism of trans-placental dissemination of ZIKV remains unknown. Here, we sought to determine whether monocytes, which can cross tissue barriers, assist ZIKV dissemination to the fetus. We determined this by infecting monocy...

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Detalles Bibliográficos
Autores principales: Khaiboullina, S. F., Uppal, T., Sarkar, R., Gorzalski, A., St Jeor, S., Verma, S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700238/
https://www.ncbi.nlm.nih.gov/pubmed/29167459
http://dx.doi.org/10.1038/s41598-017-16072-3