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Clinical risk stratification of paediatric renal transplant recipients using C1q and C3d fixing of de novo donor-specific antibodies

INTRODUCTION: We have previously shown that children who developed de novo donor-specific human leukocyte antigen (HLA) antibodies (DSA) had greater decline in allograft function. We hypothesised that patients with complement-activating DSA would have poorer renal allograft outcomes. METHODS: A tota...

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Detalles Bibliográficos
Autores principales: Kim, Jon Jin, Shaw, Olivia, Martin, Chloe, Michaelides, George, Balasubramaniam, Ramnath, Sebire, Neil J., Mamode, Nizam, Dorling, Anthony, Vaughan, Robert, Marks, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700253/
https://www.ncbi.nlm.nih.gov/pubmed/28918487
http://dx.doi.org/10.1007/s00467-017-3772-7