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PKCδ silencing alleviates saturated fatty acid induced ER stress by enhancing SERCA activity

Protein kinase C δ (PKCδ) plays an important role in nonalcoholic fatty liver disease (NAFLD), however, the mechanism remains unknown. The present study explored the role of PKCδ in NAFLD development and investigated the relationships between PKCδ, calcium homeostasis, and endoplasmic reticulum (ER)...

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Detalles Bibliográficos
Autores principales: Lai, Shujie, Li, Yan, Kuang, Yi, Cui, Hongli, Yang, Yang, Sun, Wenjing, Liu, Kaijun, Chen, Dongfeng, Yan, Qixian, Wen, Liangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700272/
https://www.ncbi.nlm.nih.gov/pubmed/29046367
http://dx.doi.org/10.1042/BSR20170869