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Suppression of Stim1 reduced intracellular calcium concentration and attenuated hypoxia/reoxygenation induced apoptosis in H9C2 cells

Objective: Previous studies have demonstrated Stromal interaction molecule 1 (STIM1)-mediated store-operated Ca(2+) entry (SOCE) contributes to intracellular Ca(2+) accumulation. The present study aimed to investigate the expression of STIM1 and its downstream molecules Orai1/TRPC1 in the context of...

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Detalles Bibliográficos
Autores principales: He, Fei, Wu, Qianfu, Xu, Banglong, Wang, Xiaocheng, Wu, Jixiong, Huang, Li, Cheng, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700273/
https://www.ncbi.nlm.nih.gov/pubmed/29089467
http://dx.doi.org/10.1042/BSR20171249