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Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture

Disc nucleus pulposus (NP) matrix homeostasis is important for normal disc function. Mechanical overloading seriously decreases matrix synthesis and increases matrix degradation. The present study aims to investigate the effects of resveratrol on disc NP matrix homeostasis under a relatively high-ma...

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Detalles Bibliográficos
Autores principales: Han, Xiaorui, Leng, Xiaoming, Zhao, Man, Wu, Mei, Chen, Amei, Hong, Guoju, Sun, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700294/
https://www.ncbi.nlm.nih.gov/pubmed/29074559
http://dx.doi.org/10.1042/BSR20171319