Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats

Quantitative whole-body autoradiography was used to assess the distribution and tissue penetration of isavuconazole in rats following single and repeated oral-dose administration of radiolabeled isavuconazonium sulfate, the prodrug of isavuconazole. Following a single-dose administration of radiolab...

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Detalles Bibliográficos
Autores principales: Schmitt-Hoffmann, Anne-Hortense, Kato, Kota, Townsend, Robert, Potchoiba, Michael J., Hope, William W., Andes, David, Spickermann, Jochen, Schneidkraut, Marlowe J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700325/
https://www.ncbi.nlm.nih.gov/pubmed/28971866
http://dx.doi.org/10.1128/AAC.01292-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700325/
https://www.ncbi.nlm.nih.gov/pubmed/28971866
http://dx.doi.org/10.1128/AAC.01292-17

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