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Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement

Recent work has introduced a new fluorescent voltage sensor, ASAP1, which can monitor rapid trains of action potentials in cultured neurons. This indicator is based on the Gallus gallus voltage-sensitive phosphatase with the phosphatase domain removed and a circularly permuted GFP placed in the S3-S...

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Detalles Bibliográficos
Autores principales: Lee, Elizabeth E.L., Bezanilla, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700382/
https://www.ncbi.nlm.nih.gov/pubmed/29108650
http://dx.doi.org/10.1016/j.bpj.2017.10.018