Absolute Quantification of Amyloid Propagons by Digital Microfluidics

[Image: see text] The self-replicating properties of proteins into amyloid fibrils is a common phenomenon and underlies a variety of neurodegenerative diseases. Because propagation-active fibrils are chemically indistinguishable from innocuous aggregates and monomeric precursors, their detection req...

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Detalles Bibliográficos
Autores principales: Pfammatter, Manuela, Andreasen, Maria, Meisl, Georg, Taylor, Christopher G., Adamcik, Jozef, Bolisetty, Sreenath, Sánchez-Ferrer, Antoni, Klenerman, David, Dobson, Christopher M., Mezzenga, Raffaele, Knowles, Tuomas P. J., Aguzzi, Adriano, Hornemann, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700450/
https://www.ncbi.nlm.nih.gov/pubmed/28972786
http://dx.doi.org/10.1021/acs.analchem.7b03279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700450/
https://www.ncbi.nlm.nih.gov/pubmed/28972786
http://dx.doi.org/10.1021/acs.analchem.7b03279

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