In Situ Ligation of High‐ and Low‐Affinity Ligands to Cell Surface Receptors Enables Highly Selective Recognition

This paper reports an entirely unexplored concept of simultaneously recognizing two receptors using high‐ and low‐affinity ligands through ligating them in situ on the target cell surface. This de novo approach is inspired by the pretargeting strategy frequently applied in molecular imaging, and has...

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Detalles Bibliográficos
Autores principales: Taichi, Misako, Nomura, Shogo, Nakase, Ikuhiko, Imamaki, Rie, Kizuka, Yasuhiko, Ota, Fumi, Dohmae, Naoshi, Kitazume, Shinobu, Taniguchi, Naoyuki, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700463/
https://www.ncbi.nlm.nih.gov/pubmed/29201607
http://dx.doi.org/10.1002/advs.201700147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700463/
https://www.ncbi.nlm.nih.gov/pubmed/29201607
http://dx.doi.org/10.1002/advs.201700147

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