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Stabilized β-Catenin Ameliorates ALPS-Like Symptoms of B6/lpr Mice

Autoimmune lymphoproliferative syndrome (ALPS) is an incurable disease mainly caused by the defect of Fas-mediated apoptosis and characterized by nonmalignant autoimmune lymphoproliferation. Stabilized β-catenin could not only potentiate Fas-mediated T cell apoptosis via upregulating the expression...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoxie, Huang, Jun, Zhao, Mei, Chen, Huanpeng, Mo, Jinhua, Zhou, Xiaoqing, Su, Qiao, Yu, Bolan, Huang, Zhaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700472/
https://www.ncbi.nlm.nih.gov/pubmed/29250557
http://dx.doi.org/10.1155/2017/3469108