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On Characterizing the Interactions between Proteins and Guanine Quadruplex Structures of Nucleic Acids

Guanine quadruplexes (G4s) are four-stranded secondary structures of nucleic acids which are stabilized by noncanonical hydrogen bonding systems between the nitrogenous bases as well as extensive base stacking, or pi-pi, interactions. Formation of these structures in either genomic DNA or cellular R...

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Detalles Bibliográficos
Autores principales: McRae, Ewan K. S., Booy, Evan P., Padilla-Meier, Gay Pauline, McKenna, Sean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700478/
https://www.ncbi.nlm.nih.gov/pubmed/29250441
http://dx.doi.org/10.1155/2017/9675348