PD-L1 Promotes Self-Renewal and Tumorigenicity of Malignant Melanoma Initiating Cells

Recent studies have indicated that therapeutic antibodies targeting PD-L1 show remarkable efficacy in clinical trials in multiple tumors and that a melanoma cell-intrinsic PD-1: PD-L1 axis promotes tumor growth. However, few studies have shown tumor-intrinsic PD-L1 effects in malignant melanoma init...

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Detalles Bibliográficos
Autores principales: Zheng, Fang, Dang, Jianzhong, Zha, Hui, Zhang, Bingyu, Lin, Ming, Cheng, Fanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700500/
https://www.ncbi.nlm.nih.gov/pubmed/29250533
http://dx.doi.org/10.1155/2017/1293201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700500/
https://www.ncbi.nlm.nih.gov/pubmed/29250533
http://dx.doi.org/10.1155/2017/1293201

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