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PD-L1 Promotes Self-Renewal and Tumorigenicity of Malignant Melanoma Initiating Cells

Recent studies have indicated that therapeutic antibodies targeting PD-L1 show remarkable efficacy in clinical trials in multiple tumors and that a melanoma cell-intrinsic PD-1: PD-L1 axis promotes tumor growth. However, few studies have shown tumor-intrinsic PD-L1 effects in malignant melanoma init...

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Detalles Bibliográficos
Autores principales:	Zheng, Fang, Dang, Jianzhong, Zha, Hui, Zhang, Bingyu, Lin, Ming, Cheng, Fanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700500/ https://www.ncbi.nlm.nih.gov/pubmed/29250533 http://dx.doi.org/10.1155/2017/1293201

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