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Process optimization for enhancing production of cis-4-hydroxy-l-proline by engineered Escherichia coli
BACKGROUND: Understanding the bioprocess limitations is critical for the efficient design of biocatalysts to facilitate process feasibility and improve process economics. In this study, a proline hydroxylation process with recombinant Escherichia coli expressing l-proline cis-4-hydroxylase (SmP4H) w...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700529/ https://www.ncbi.nlm.nih.gov/pubmed/29166916 http://dx.doi.org/10.1186/s12934-017-0821-7 |