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Process optimization for enhancing production of cis-4-hydroxy-l-proline by engineered Escherichia coli

BACKGROUND: Understanding the bioprocess limitations is critical for the efficient design of biocatalysts to facilitate process feasibility and improve process economics. In this study, a proline hydroxylation process with recombinant Escherichia coli expressing l-proline cis-4-hydroxylase (SmP4H) w...

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Detalles Bibliográficos
Autores principales:	Chen, Kequan, Pang, Yang, Zhang, Bowen, Feng, Jiao, Xu, Sheng, Wang, Xin, Ouyang, Pingkai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700529/ https://www.ncbi.nlm.nih.gov/pubmed/29166916 http://dx.doi.org/10.1186/s12934-017-0821-7

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