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Similar short-term clinical response to high-dose versus low-dose methotrexate in monotherapy and combination therapy in patients with rheumatoid arthritis

BACKGROUND: Aiming at rapid decrease of disease activity, there has been a trend to start with higher doses of methotrexate (MTX) in patients newly diagnosed with rheumatoid arthritis (RA), both as monotherapy and in combination with other antirheumatic drugs. We aimed to study the relationship betw...

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Detalles Bibliográficos
Autores principales: Bergstra, Sytske Anne, Allaart, Cornelia F., van den Berg, Rosaline, Chopra, Arvind, Govind, Nimmisha, Huizinga, Tom W. J., Landewe, Robert B. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700534/
https://www.ncbi.nlm.nih.gov/pubmed/29166919
http://dx.doi.org/10.1186/s13075-017-1468-9