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BAP1: case report and insight into a novel tumor suppressor

BACKGROUND: BRCA1-Associated-Protein 1 (BAP1) is a dynamic tumor suppressor which, when mutated, has been associated with an increased risk of uveal melanoma, cutaneous melanoma, mesothelioma, and several other cancers. Germline BAP1 mutations have been extensively studied, where they have been foun...

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Detalles Bibliográficos
Autores principales: Ghosh, Kanad, Modi, Badri, James, William D., Capell, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700555/
https://www.ncbi.nlm.nih.gov/pubmed/29166932
http://dx.doi.org/10.1186/s12895-017-0065-6