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vWF/ADAMTS13 is associated with on-aspirin residual platelet reactivity and clinical outcome in patients with stable coronary artery disease

BACKGROUND: The mechanisms behind residual platelet reactivity (RPR) despite aspirin treatment are not established. It has been shown that coronary artery disease (CAD) patients with high on-aspirin RPR have elevated levels of von Willebrand factor (vWF). ADAMTS13 is a metalloprotease cleaving ultra...

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Detalles Bibliográficos
Autores principales: Warlo, Ellen M. K., Pettersen, Alf-Åge R., Arnesen, Harald, Seljeflot, Ingebjørg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700557/
https://www.ncbi.nlm.nih.gov/pubmed/29200971
http://dx.doi.org/10.1186/s12959-017-0151-3