Mitochondrial genetics and therapeutic overview of Leber's hereditary optic neuropathy

Leber's hereditary optic neuropathy (LHON) is a common inherited mitochondrial disorder that is characterized by the degeneration of the optic nerves, leading to vision loss. The major mutations in the mitochondrial genes ND1, ND4, and ND6 of LHON subjects are found to increase the oxidative st...

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Detalles Bibliográficos
Autores principales: Manickam, Agaath Hedina, Michael, Minu Jenifer, Ramasamy, Sivasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700573/
https://www.ncbi.nlm.nih.gov/pubmed/29133631
http://dx.doi.org/10.4103/ijo.IJO_358_17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700573/
https://www.ncbi.nlm.nih.gov/pubmed/29133631
http://dx.doi.org/10.4103/ijo.IJO_358_17

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