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Genome Editing for Cancer Therapy: Delivery of Cas9 Protein/sgRNA Plasmid via a Gold Nanocluster/Lipid Core–Shell Nanocarrier

The type II bacterial clustered, regularly interspaced, short palindromic repeats (CRISPR)‐Cas9 (CRISPR‐associated protein) system (CRISPR‐Cas9) is a powerful toolbox for gene‐editing, however, the nonviral delivery of CRISPR‐Cas9 to cells or tissues remains a key challenge. This paper reports a str...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Zhang, Lingmin, Xie, Yangzhouyun, Wang, Nuoxin, Tang, Rongbing, Zheng, Wenfu, Jiang, Xingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700650/
https://www.ncbi.nlm.nih.gov/pubmed/29201613
http://dx.doi.org/10.1002/advs.201700175