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Advanced glycation endproducts link inflammatory cues to upregulation of galectin-1 in diabetic retinopathy

Diabetic retinopathy (DR) is an inflammatory and progressive vaso-occlusive disease resulting in angiogenesis. Galectin-1 is a hypoxia-induced angiogenic factor associated with cancer and proliferative DR. Here we reveal a significant upregulation of galectin-1 in eyes of DR patients along with prog...

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Detalles Bibliográficos
Autores principales: Kanda, Atsuhiro, Dong, Yoko, Noda, Kousuke, Saito, Wataru, Ishida, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700925/
https://www.ncbi.nlm.nih.gov/pubmed/29170525
http://dx.doi.org/10.1038/s41598-017-16499-8