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Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori

The Helicobacter pylori phase variable gene modH, typified by gene HP1522 in strain 26695, encodes a N(6)-adenosine type III DNA methyltransferase. Our previous studies identified multiple strain-specific modH variants (modH1 – modH19) and showed that phase variation of modH5 in H. pylori P12 influe...

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Detalles Bibliográficos
Autores principales: Srikhanta, Yogitha N., Gorrell, Rebecca J., Power, Peter M., Tsyganov, Kirill, Boitano, Matthew, Clark, Tyson A., Korlach, Jonas, Hartland, Elizabeth L., Jennings, Michael P., Kwok, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700931/
https://www.ncbi.nlm.nih.gov/pubmed/29170397
http://dx.doi.org/10.1038/s41598-017-15721-x