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T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because attempts to target tumors directly have yielded limited benefit, we instead target endogenous immune cell subsets in the circulation that can migrat...

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Detalles Bibliográficos
Autores principales: Schmid, Daniela, Park, Chun Gwon, Hartl, Christina A., Subedi, Nikita, Cartwright, Adam N., Puerto, Regina Bou, Zheng, Yiran, Maiarana, James, Freeman, Gordon J., Wucherpfennig, Kai W., Irvine, Darrell J., Goldberg, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700944/
https://www.ncbi.nlm.nih.gov/pubmed/29170511
http://dx.doi.org/10.1038/s41467-017-01830-8