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Non-Invasive whole-body detection of complement activation using radionuclide imaging in a mouse model of myocardial ischaemia-reperfusion injury

Complement activation is a recognised mediator of myocardial ischaemia-reperfusion-injury (IRI) and cardiomyocytes are a known source of complement proteins including the central component C3, whose activation products can mediate tissue inflammation, cell death and profibrotic signalling. We invest...

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Detalles Bibliográficos
Autores principales: Sharif-Paghaleh, Ehsan, Yap, May Lin, Puhl, Sarah-Lena, Badar, Adam, Torres, Julia Baguña, Chuamsaamarkkee, Krisanat, Kampmeier, Florian, Smith, Richard A., Clark, James, Blower, Philip J., Sacks, Steven, Mullen, Gregory E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700950/
https://www.ncbi.nlm.nih.gov/pubmed/29170426
http://dx.doi.org/10.1038/s41598-017-16387-1