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Equilibrium folding dynamics of meACP in water, heavy water, and low concentration of urea

Many proteins fold in apparent two-state behavior, as partially folded intermediates only transiently accumulate and easily escape detection. Besides a native form and a mainly unfolded form, we captured a partially unfolded form of an acyl carrier protein from Micromonospora echinospora (meACP) in...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Yang, Daiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700953/
https://www.ncbi.nlm.nih.gov/pubmed/29170533
http://dx.doi.org/10.1038/s41598-017-16449-4