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Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis
Histone lysine methyltransferases (KMTs) represent an important class of epigenetic enzymes that play essential roles in regulation of gene expression in humans. Members of the KMT family catalyze the transfer of the methyl group from S-adenosylmethionine (SAM) to lysine residues in histone tails an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700997/ https://www.ncbi.nlm.nih.gov/pubmed/29170487 http://dx.doi.org/10.1038/s41598-017-16128-4 |