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Lysine Possesses the Optimal Chain Length for Histone Lysine Methyltransferase Catalysis

Histone lysine methyltransferases (KMTs) represent an important class of epigenetic enzymes that play essential roles in regulation of gene expression in humans. Members of the KMT family catalyze the transfer of the methyl group from S-adenosylmethionine (SAM) to lysine residues in histone tails an...

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Detalles Bibliográficos
Autores principales: Temimi, Abbas H. K. Al, Reddy, Y. Vijayendar, White, Paul B., Guo, Hong, Qian, Ping, Mecinović, Jasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700997/
https://www.ncbi.nlm.nih.gov/pubmed/29170487
http://dx.doi.org/10.1038/s41598-017-16128-4