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Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer

The new oncologic paradigm of precision medicine is focused on identifying metabolic, proteomic, transcriptomic and genomic variabilities in tumors that can be exploited to tailor treatments and improve patient outcomes. Metabolic changes are a hallmark of cancer, and inhibition of metabolic pathway...

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Detalles Bibliográficos
Autores principales: Zacharias, Niki Marie, McCullough, Christopher, Shanmugavelandy, Sriram, Lee, Jaehyuk, Lee, Youngbok, Dutta, Prasanta, McHenry, James, Nguyen, Linda, Norton, William, Jones, Lawrence W., Bhattacharya, Pratip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701017/
https://www.ncbi.nlm.nih.gov/pubmed/29170516
http://dx.doi.org/10.1038/s41598-017-16327-z