Host STING-dependent MDSC mobilization drives extrinsic radiation resistance

Radiotherapy induces and promotes innate and adaptive immunity in which host STING plays an important role. However, radioresistance in irradiated tumors can also develop, resulting in relapse. Here we report a mechanism by which extrinsic resistance develops after local ablative radiation that reli...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Hua, Deng, Liufu, Hou, Yuzhu, Meng, Xiangjiao, Huang, Xiaona, Rao, Enyu, Zheng, Wenxin, Mauceri, Helena, Mack, Matthias, Xu, Meng, Fu, Yang-Xin, Weichselbaum, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701019/
https://www.ncbi.nlm.nih.gov/pubmed/29170400
http://dx.doi.org/10.1038/s41467-017-01566-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701019/
https://www.ncbi.nlm.nih.gov/pubmed/29170400
http://dx.doi.org/10.1038/s41467-017-01566-5

Ejemplares similares