p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function

Homeodomain-interacting protein kinase 2 (HIPK2) is a nuclear serine/threonine kinase that functions in development and tumor suppression. One of the prominent features of this kinase is that it is tightly regulated by proteasomal degradation. In the present study, we present evidence suggesting tha...

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Detalles Bibliográficos
Autores principales: Choi, Jong-Ryoul, Lee, Seo-Young, Shin, Ki Soon, Choi, Cheol Yong, Kang, Shin Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701035/
https://www.ncbi.nlm.nih.gov/pubmed/29170424
http://dx.doi.org/10.1038/s41598-017-16489-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701035/
https://www.ncbi.nlm.nih.gov/pubmed/29170424
http://dx.doi.org/10.1038/s41598-017-16489-w

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