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p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function
Homeodomain-interacting protein kinase 2 (HIPK2) is a nuclear serine/threonine kinase that functions in development and tumor suppression. One of the prominent features of this kinase is that it is tightly regulated by proteasomal degradation. In the present study, we present evidence suggesting tha...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701035/ https://www.ncbi.nlm.nih.gov/pubmed/29170424 http://dx.doi.org/10.1038/s41598-017-16489-w |