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Systems analysis of latent HIV reversal reveals altered stress kinase signaling and increased cell death in infected T cells
Viral latency remains the most significant obstacle to HIV eradication. Clinical strategies aim to purge the latent CD4+ T cell reservoir by activating viral expression to induce death, but are undercut by the inability to target latently infected cells. Here we explored the acute signaling response...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701066/ https://www.ncbi.nlm.nih.gov/pubmed/29170390 http://dx.doi.org/10.1038/s41598-017-15532-0 |