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Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial–mesenchymal transition by inducing 14-3-3γ expression

Metastatic cancer cells acquire energy-intensive processes including increased invasiveness and chemoresistance. However, how the energy demand is met and the molecular drivers that coordinate an increase in cellular metabolic activity to drive epithelial–mesenchymal transition (EMT), the first step...

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Detalles Bibliográficos
Autores principales: Teo, Z, Sng, M K, Chan, J S K, Lim, M M K, Li, Y, Li, L, Phua, T, Lee, J Y H, Tan, Z W, Zhu, P, Tan, N S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701092/
https://www.ncbi.nlm.nih.gov/pubmed/28745316
http://dx.doi.org/10.1038/onc.2017.244