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Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells

The adenylate cyclase toxin (CyaA) of the whooping cough agent Bordetella pertussis subverts immune functions of host myeloid cells expressing the α(M)β(2) integrin (CD11b/CD18, CR3 or Mac-1). CyaA delivers into cytosol of cells an extremely catalytically active adenylyl cyclase enzyme, which disrup...

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Detalles Bibliográficos
Autores principales: Novák, Jakub, Fabrik, Ivo, Linhartová, Irena, Link, Marek, Černý, Ondřej, Stulík, Jiří, Šebo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701129/
https://www.ncbi.nlm.nih.gov/pubmed/29176673
http://dx.doi.org/10.1038/s41598-017-14501-x