Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4

Jumonji domain-containing protein 6 (JMJD6) is a member of the Jumonji C family of Fe(II) and 2-oxoglutarate (2OG) dependent oxygenases. It possesses unique bi-functional oxygenase activities, acting as both an arginine demethylase and a lysyl-hydroxylase. JMJD6 has been reported to be over-expresse...

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Detalles Bibliográficos
Autores principales: Konuma, Tsuyoshi, Yu, Di, Zhao, Chengcheng, Ju, Ying, Sharma, Rajal, Ren, Chunyan, Zhang, Qiang, Zhou, Ming-Ming, Zeng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701133/
https://www.ncbi.nlm.nih.gov/pubmed/29176719
http://dx.doi.org/10.1038/s41598-017-16588-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701133/
https://www.ncbi.nlm.nih.gov/pubmed/29176719
http://dx.doi.org/10.1038/s41598-017-16588-8

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