Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Glaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy. Our study helps to better understand underlying genetic...

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Detalles Bibliográficos
Autores principales: Chintalapudi, Sumana R., Maria, Doaa, Di Wang, Xiang, Bailey, Jessica N. Cooke, Hysi, Pirro G., Wiggs, Janey L., Williams, Robert W., Jablonski, Monica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701146/
https://www.ncbi.nlm.nih.gov/pubmed/29176626
http://dx.doi.org/10.1038/s41467-017-00837-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701146/
https://www.ncbi.nlm.nih.gov/pubmed/29176626
http://dx.doi.org/10.1038/s41467-017-00837-5

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