The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

While amyloid-β protein (Aβ) aggregation into insoluble plaques is one of the pathological hallmarks of Alzheimer’s disease (AD), soluble oligomeric Aβ has been hypothesized to be responsible for synapse damage, neurodegeneration, learning, and memory deficits in AD. Here, we investigate the in vitr...

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Detalles Bibliográficos
Autores principales: van Groen, Thomas, Schemmert, Sarah, Brener, Oleksandr, Gremer, Lothar, Ziehm, Tamar, Tusche, Markus, Nagel-Steger, Luitgard, Kadish, Inga, Schartmann, Elena, Elfgen, Anne, Jürgens, Dagmar, Willuweit, Antje, Kutzsche, Janine, Willbold, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701182/
https://www.ncbi.nlm.nih.gov/pubmed/29176708
http://dx.doi.org/10.1038/s41598-017-16565-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701182/
https://www.ncbi.nlm.nih.gov/pubmed/29176708
http://dx.doi.org/10.1038/s41598-017-16565-1

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