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Plasma cell survival in the absence of B cell memory

Pre-existing serum antibodies play an important role in vaccine-mediated protection against infection but the underlying mechanisms of immune memory are unclear. Clinical studies indicate that antigen-specific antibody responses can be maintained for many years, leading to theories that reactivation...

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Detalles Bibliográficos
Autores principales: Hammarlund, Erika, Thomas, Archana, Amanna, Ian J., Holden, Lindsay A., Slayden, Ov D., Park, Byung, Gao, Lina, Slifka, Mark K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701209/
https://www.ncbi.nlm.nih.gov/pubmed/29176567
http://dx.doi.org/10.1038/s41467-017-01901-w