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Notoginsenoside R1 Alleviates Oxygen–Glucose Deprivation/Reoxygenation Injury by Suppressing Endoplasmic Reticulum Calcium Release via PLC

As documented in our previous study, notoginsenoside R1 (NGR1) can inhibit neuron apoptosis and the expression of endoplasmic reticulum (ER) stress-associated pro-apoptotic proteins in hypoxic–ischemic encephalopathy. Recent evidence indicates that the Phospholipase C (PLC)/inositol 1,4,5-trisphosph...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Tu, Liu, Li, Yingbo, Chen, Di, Liu, Zhao, Hu, Xuelian, Wang, Shali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701215/
https://www.ncbi.nlm.nih.gov/pubmed/29176553
http://dx.doi.org/10.1038/s41598-017-16373-7