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NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis

Squamous cell carcinomas of the head and neck (SCCHN) affect anatomical sites including the oral cavity, nasal cavity, pharynx, and larynx. Laryngeal cancers are characterized by high recurrence and poor overall survival, and currently lack robust molecular prognostic biomarkers for treatment strati...

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Detalles Bibliográficos
Autores principales: Peri, Suraj, Izumchenko, Evgeny, Schubert, Adrian D., Slifker, Michael J., Ruth, Karen, Serebriiskii, Ilya G., Guo, Theresa, Burtness, Barbara A., Mehra, Ranee, Ross, Eric A., Sidransky, David, Golemis, Erica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701248/
https://www.ncbi.nlm.nih.gov/pubmed/29176703
http://dx.doi.org/10.1038/s41467-017-01877-7