The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence

Pseudomonas phage LKA1 of the subfamily Autographivirinae encodes a tailspike protein (LKA1gp49) which binds and cleaves B-band LPS (O-specific antigen, OSA) of Pseudomonas aeruginosa PAO1. The crystal structure of LKA1gp49 catalytic domain consists of a beta-helix, an insertion domain and a C-termi...

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Detalles Bibliográficos
Autores principales: Olszak, Tomasz, Shneider, Mikhail M., Latka, Agnieszka, Maciejewska, Barbara, Browning, Christopher, Sycheva, Lada V., Cornelissen, Anneleen, Danis-Wlodarczyk, Katarzyna, Senchenkova, Sofya N., Shashkov, Alexander S., Gula, Grzegorz, Arabski, Michal, Wasik, Slawomir, Miroshnikov, Konstantin A., Lavigne, Rob, Leiman, Petr G., Knirel, Yuriy A., Drulis-Kawa, Zuzanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701251/
https://www.ncbi.nlm.nih.gov/pubmed/29176754
http://dx.doi.org/10.1038/s41598-017-16411-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701251/
https://www.ncbi.nlm.nih.gov/pubmed/29176754
http://dx.doi.org/10.1038/s41598-017-16411-4

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