Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagy

Endoplasmic reticulum (ER) and lysosomes coordinate a network of key cellular processes including unfolded protein response (UPR) and autophagy in response to stress. How ER stress is signaled to lysosomes remains elusive. Here we find that ER disturbance activates chaperone-mediated autophagy (CMA)...

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Detalles Bibliográficos
Autores principales: Li, Wenming, Zhu, Jinqiu, Dou, Juan, She, Hua, Tao, Kai, Xu, Haidong, Yang, Qian, Mao, Zixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701254/
https://www.ncbi.nlm.nih.gov/pubmed/29176575
http://dx.doi.org/10.1038/s41467-017-01609-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701254/
https://www.ncbi.nlm.nih.gov/pubmed/29176575
http://dx.doi.org/10.1038/s41467-017-01609-x

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