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A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens

BACKGROUND: Tuberculosis kills more people than any other infectious disease, and new regimens are essential. The primary endpoint for confirmatory phase III trials for new regimens is a composite outcome that includes bacteriological treatment failure and relapse. Culture methodology is critical to...

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Detalles Bibliográficos
Autores principales: Phillips, Patrick P. J., Mendel, Carl M., Nunn, Andrew J., McHugh, Timothy D., Crook, Angela M., Hunt, Robert, Bateson, Anna, Gillespie, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701316/
https://www.ncbi.nlm.nih.gov/pubmed/29169355
http://dx.doi.org/10.1186/s12916-017-0955-9