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In silico design of a Zika virus non-structural protein 5 aiming vaccine protection against zika and dengue in different human populations
BACKGROUND: The arboviruses Zika virus (ZIKV) and Dengue virus (DENV) have important epidemiological impact in Brazil and other tropical regions of the world. Recently, it was shown that previous humoral immunity to DENV enhances ZIKV replication in vitro, which may lead to more severe forms of the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701345/ https://www.ncbi.nlm.nih.gov/pubmed/29169357 http://dx.doi.org/10.1186/s12929-017-0395-z |