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Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer

BACKGROUND: Epigenetic alterations are strongly associated with the development of cancer. The aim of this study was to identify epigenetic pattern in squamous cell lung cancer (LUSC) on a genome-wide scale. RESULTS: Here we performed DNA methylation profiling on 24 LUSC and paired non-tumor lung (N...

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Detalles Bibliográficos
Autores principales: Shi, Yuan-Xiang, Wang, Ying, Li, Xi, Zhang, Wei, Zhou, Hong-Hao, Yin, Ji-Ye, Liu, Zhao-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701423/
https://www.ncbi.nlm.nih.gov/pubmed/29169318
http://dx.doi.org/10.1186/s12864-017-4223-3